Issue 4, 2005
From the journal:

Organic & Biomolecular Chemistry

Fluorescence enhancement of bis-acridine orange peptide, BAO, upon binding to double stranded DNA†

Keiji Mizuki,a   Yutaka Sakakibara,a   Hiroyuki Ueyama,a   Takahiko Nojima,a   Michinori Wakia  and  Shigeori Takenaka*a  

* Corresponding authors

a Department of Applied Chemistry, Faculty of Engineering, Kyushu University, Fukuoka, Japan
E-mail: staketcm@mbox.nc.kyushu-u.ac.jp

Abstract

Bis-acridine orange peptides carrying two acridine oranges at the ε-amino moieties of both terminal lysines of a tetra(lysine) chain showed a ca. 200-fold fluorescence enhancement upon addition of double stranded DNA.

Graphical abstract: Fluorescence enhancement of bis-acridine orange peptide, BAO, upon binding to double stranded DNA

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Article information

DOI
https://doi.org/10.1039/B417391K
Article type
Communication
Submitted
16 Nov 2004
Accepted
20 Dec 2004
First published
13 Jan 2005

Org. Biomol. Chem., 2005,3, 578-580

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Fluorescence enhancement of bis-acridine orange peptide, BAO, upon binding to double stranded DNA

K. Mizuki, Y. Sakakibara, H. Ueyama, T. Nojima, M. Waki and S. Takenaka, Org. Biomol. Chem., 2005, 3, 578 DOI: 10.1039/B417391K

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