Issue 12, 2005
From the journal:

Organic & Biomolecular Chemistry

Solution conformation of d(C4ACAC4TGT)2; an intramolecularly folded i-motif from the insulin minisatellite†

Vandana V. Jolad,a   Fatima K. Murad,a   John R. P. Arnolda  and  Julie Fisher*a  

* Corresponding authors

a School of Chemistry, University of Leeds, Leeds, UK
E-mail: j.fisher@chem.leeds.ac.uk
Fax: +44 (0)113 34 36565
Tel: +44 (0)113 34 36577

Abstract

A 28-mer sequence taken from the insulin minisatellite is shown, through NMR and UV thermal melting studies, to form an intramolecular i-motif with two ACA and one TGT loop that persists to near neutral pH and room temperature.

Graphical abstract: Solution conformation of d(C4ACAC4TGT)2; an intramolecularly folded i-motif from the insulin minisatellite

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Article information

DOI
https://doi.org/10.1039/B504606H
Article type
Communication
Submitted
04 Apr 2005
Accepted
28 Apr 2005
First published
05 May 2005

Org. Biomol. Chem., 2005,3, 2234-2236

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Solution conformation of d(C4ACAC4TGT)2; an intramolecularly folded i-motif from the insulin minisatellite

V. V. Jolad, F. K. Murad, J. R. P. Arnold and J. Fisher, Org. Biomol. Chem., 2005, 3, 2234 DOI: 10.1039/B504606H

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