Issue 6, 2006
From the journal:

Chemical Communications

Isoindoles and dihydroisoquinolines by gold-catalyzed intramolecular hydroamination of alkynes

Daniel Kadzimirsz,a   Dirk Hildebrandt,a   Klaus Merza  and  Gerald Dyker*a  

* Corresponding authors

a Fakultät für Chemie, Ruhr-Universität Bochum, Universitätsstrasse 150, Bochum, Germany
E-mail: Gerald.Dyker@rub.de
Fax: +49 (0)234/32-14353
Tel: +49 (0)234/32-24551

Abstract

The title compounds are enantioselectively synthesized in just two prepararative steps, making use of the Ugi-four-component reaction with an amino acid as chiral component, followed by a gold-catalyzed hydroamination.

Graphical abstract: Isoindoles and dihydroisoquinolines by gold-catalyzed intramolecular hydroamination of alkynes

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Article information

DOI
https://doi.org/10.1039/B516017K
Article type
Communication
Submitted
11 Nov 2005
Accepted
19 Dec 2005
First published
12 Jan 2006

Chem. Commun., 2006, 661-662

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Isoindoles and dihydroisoquinolines by gold-catalyzed intramolecular hydroamination of alkynes

D. Kadzimirsz, D. Hildebrandt, K. Merz and G. Dyker, Chem. Commun., 2006, 661 DOI: 10.1039/B516017K

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