Asymmetric aldol reactions catalyzed by tryptophan in water†
Abstract
Tryptophan was shown to be able to catalyze direct aldol reactions between various cyclic ketones and aromatic aldehydes in water with high enantioselectivity.
* Corresponding authors
a
Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore, Republic of Singapore
E-mail:
chmlyx@nus.edu.sg
Fax: +65-6779-1691
Tel: +65-6516-1569
b The Medicinal Chemistry Program, Office of Life Sciences, National University of Singapore, Republic of Singapore
Tryptophan was shown to be able to catalyze direct aldol reactions between various cyclic ketones and aromatic aldehydes in water with high enantioselectivity.
Z. Jiang, Z. Liang, X. Wu and Y. Lu, Chem. Commun., 2006, 2801 DOI: 10.1039/B606154K
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