Issue 19, 2006
From the journal:

Organic & Biomolecular Chemistry

An efficient one-pot, three-component synthesis of indeno[1,2-b]quinoline-9,11(6H,10H)-dione, acridine-1,8(2H,5H)-dione and quinoline-3-carbonitrile derivatives from enaminones†

Shu-Jiang Tu,*a   Bo Jiang,a   Run-Hong Jia,a   Jun-Yong Zhang,a   Yan Zhang,a   Chang-Sheng Yaoa  and  Feng Shia  

* Corresponding authors

a Department of Chemistry, Xuzhou Normal University, Key Laboratory of Biotechnology for Medicinal Plant Xuzhou, Jiangsu, P.R. China
E-mail: laotu@xznu.edu.cn
Fax: +86 516 83403164
Tel: +86 516 83500349

Abstract

An efficient one-pot, three-component method for the preparation of indeno[1,2-b]quinoline-9,11(6H,10H)-dione, acridine-1,8(2H,5H)-dione and various multi-substituted quinoline-3-carbonitrile derivatives has been developed through the Michael addition to enaminones, which was achieved by both microwave irradiation and conventional heating.

Graphical abstract: An efficient one-pot, three-component synthesis of indeno[1,2-b]quinoline-9,11(6H,10H)-dione, acridine-1,8(2H,5H)-dione and quinoline-3-carbonitrile derivatives from enaminones

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Article information

DOI
https://doi.org/10.1039/B607575D
Article type
Paper
Submitted
30 May 2006
Accepted
03 Aug 2006
First published
17 Aug 2006

Org. Biomol. Chem., 2006,4, 3664-3668

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An efficient one-pot, three-component synthesis of indeno[1,2-b]quinoline-9,11(6H,10H)-dione, acridine-1,8(2H,5H)-dione and quinoline-3-carbonitrile derivatives from enaminones

S. Tu, B. Jiang, R. Jia, J. Zhang, Y. Zhang, C. Yao and F. Shi, Org. Biomol. Chem., 2006, 4, 3664 DOI: 10.1039/B607575D

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