Issue 47, 2007
From the journal:

Chemical Communications

Asymmetric synthesis of (+)-cis-nemorensic acid from a chiral Diels–Alder adduct of 2,5-dimethylfuran†

Jae Yi Sim,a   Geum-Sook Hwang,b   Kyung Hwa Kim,a   Eun Mi Koa  and  Do Hyun Ryu*a  

* Corresponding authors

a Department of Chemistry, Sungkyunkwan University, Korea
E-mail: dhryu@skku.edu
Fax: +82 31 290 5976
Tel: +82 31 290 5931

b Korea Basic Science Institute, 5St, Anam-Dong, Seongbuk-Gu, Seoul, Korea

Abstract

(+)-cis-Nemorensic acid (1) was synthesized from a chiral Diels–Alder adduct (4) prepared by a catalytic enantioselective Diels–Alder reaction with 2,5-dimethylfuran and 2,2,2-trifluoroethyl acrylate.

Graphical abstract: Asymmetric synthesis of (+)-cis-nemorensic acid from a chiral Diels–Alder adduct of 2,5-dimethylfuran

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Article information

DOI
https://doi.org/10.1039/B710537A
Article type
Communication
Submitted
11 Jul 2007
Accepted
17 Sep 2007
First published
01 Oct 2007

Chem. Commun., 2007, 5064-5065

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Asymmetric synthesis of (+)-cis-nemorensic acid from a chiral Diels–Alder adduct of 2,5-dimethylfuran

J. Y. Sim, G. Hwang, K. H. Kim, E. M. Ko and D. H. Ryu, Chem. Commun., 2007, 5064 DOI: 10.1039/B710537A

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