Issue 47, 2007
From the journal:

Chemical Communications

Strong inhibition of cholera toxin binding by galactose dendrimers†

Hilbert M. Branderhorst,a   Rob M. J. Liskamp,a   Gerben M. Visserb  and  Roland J. Pieters*a  

* Corresponding authors

a Department of Medicinal Chemistry and Chemical Biology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, PO Box 80082, 3508 TB Utrecht, The Netherlands
E-mail: R.J.Pieters@uu.nl
Fax: +31 30-2536655

b Laboratory of Organic Chemistry, Wageningen University, Dreijenplein 8, 6703HB Wageningen, The Netherlands

Abstract

Galactose-containing dendrimers with long spacer arms inhibit cholera toxin binding as strongly as the natural ganglioside GM1 oligosaccharide does.

Graphical abstract: Strong inhibition of cholera toxin binding by galactose dendrimers

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Article information

DOI
https://doi.org/10.1039/B711070G
Article type
Communication
Submitted
19 Jul 2007
Accepted
07 Sep 2007
First published
24 Sep 2007

Chem. Commun., 2007, 5043-5045

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Strong inhibition of cholera toxin binding by galactose dendrimers

H. M. Branderhorst, R. M. J. Liskamp, G. M. Visser and R. J. Pieters, Chem. Commun., 2007, 5043 DOI: 10.1039/B711070G

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