Issue 5, 2007
From the journal:

Natural Product Reports

Roles of vitamins B5, B8, B9, B12 and molybdenum cofactor at cellular and organismal levels†

Fabrice Rébeillé,*a   Stéphane Ravanel,a   Andrée Marquet,b   Ralf R. Mendel,c   Alison G. Smithd  and  Martin J. Warrene  

* Corresponding authors

a Laboratoire de Physiologie Cellulaire Végétale, UMR5168, Université Joseph Fourier-CNRS-CEA-INRA, Institut de Recherche en Technologies et Sciences du Vivant, CEA-Grenoble, 17 rue des Martyrs, Grenoble, Cedex 9, France
E-mail: frebeille@cea.fr
Fax: +33 438-78-50-91
Tel: +33 438-78-44-93

b Department of Chemistry, Université Pierre et Marie Curie, UMR CNRS 7613, Paris, France
E-mail: marquet@ccr.jussieu.fr

c Department of Plant Biology, Technical University of Braunschweig, Braunschweig, Germany
E-mail: r.mendel@tu-bs.de

d Department of Plant Sciences, University of Cambridge, Cambridge, UK
E-mail: as25@cam.ac.uk

e Department of Biochemistry, University of Kent, Canterbury, UK
E-mail: m.j.warren@kent.ac.uk

Abstract

Covering: 1984 to 2007

Many efforts have been made in recent decades to understand how coenzymes, including vitamins, are synthesised in organisms. In the present review, we describe the most recent findings about the biological roles of five coenzymes: folate (vitamin B9), pantothenate (vitamin B5), cobalamin (vitamin B12), biotin (vitamin B8) and molybdenum cofactor (Moco). In the first part, we will emphasise their biological functions, including the specific roles found in some organisms. In the second part we will present some nutritional aspects and potential strategies to enhance the cofactor contents in organisms of interest.

Graphical abstract: Roles of vitamins B5, B8, B9, B12 and molybdenum cofactor at cellular and organismal levels

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Article information

DOI
https://doi.org/10.1039/B703104C
Article type
Review Article
Submitted
14 Jun 2007
First published
20 Aug 2007

Nat. Prod. Rep., 2007,24, 949-962

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Roles of vitamins B5, B8, B9, B12 and molybdenum cofactor at cellular and organismal levels

F. Rébeillé, S. Ravanel, A. Marquet, R. R. Mendel, A. G. Smith and M. J. Warren, Nat. Prod. Rep., 2007, 24, 949 DOI: 10.1039/B703104C

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