Issue 5, 2008
From the journal:

Chemical Communications

Highly shifted LIPOCEST agents based on the encapsulation of neutral polynuclear paramagnetic shift reagents†

Enzo Terreno,a   Alessandro Barge,b   Lorena Beltrami,c   Giancarlo Cravotto,b   Daniela Delli Castelli,a   Franco Fedeli,c   Bhagavathsingh Jebasingha  and  Silvio Aime*a  

* Corresponding authors

a Department of Chemisry IFM and Molecular Imaging Center, University of Torino, Via P. Giuria 7, Torino, Italy
E-mail: silvio.aime@unito.it
Fax: +39-011-6707855

b Department of Pharmaceutical Science and Technology, University of Torino, Via P. Giuria 9, Torino, Italy

c Laboratory of Advanced and Integrated Methodologies, Bioindustry Park Canavese, Via Ribes 5, Colleretto Giacosa (TO), Italy

Abstract

Improved LIPOCEST MRI contrast agents with highly shifted intraliposomal water protons were prepared by entrapping neutral polynuclear Tm(III)-based paramagnetic shift reagents in phospholipidic vesicles.

Graphical abstract: Highly shifted LIPOCEST agents based on the encapsulation of neutral polynuclear paramagnetic shift reagents

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Article information

DOI
https://doi.org/10.1039/B715383J
Article type
Communication
Submitted
08 Oct 2007
Accepted
15 Nov 2007
First published
26 Nov 2007

Chem. Commun., 2008, 600-602

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Highly shifted LIPOCEST agents based on the encapsulation of neutral polynuclear paramagnetic shift reagents

E. Terreno, A. Barge, L. Beltrami, G. Cravotto, D. D. Castelli, F. Fedeli, B. Jebasingh and S. Aime, Chem. Commun., 2008, 600 DOI: 10.1039/B715383J

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