Issue 10, 2008
From the journal:

Chemical Communications

Direct arylations on water: synthesis of 2,5-disubstituted oxazoles balsoxin and texaline†‡

Stephan A. Ohnmacht,a   Patrizia Mamone,a   Andrew J. Culshawb  and  Michael F. Greaney*a  

* Corresponding authors

a University of Edinburgh, School of Chemistry, Joseph Black Building, King’s Buildings, West Mains Rd, Edinburgh, UK

b Global Discovery Chemistry, Novartis Horsham Research Centre, Wimblehurst Road, Horsham, West Sussex, UK

Abstract

An efficient two-step palladium catalysed synthesis of 2,5-disubstituted oxazoles is reported.

Graphical abstract: Direct arylations on water: synthesis of 2,5-disubstituted oxazoles balsoxin and texaline

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Article information

DOI
https://doi.org/10.1039/B719466H
Article type
Communication
Submitted
18 Dec 2007
Accepted
18 Jan 2008
First published
05 Feb 2008

Chem. Commun., 2008, 1241-1243

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Direct arylations on water: synthesis of 2,5-disubstituted oxazoles balsoxin and texaline

S. A. Ohnmacht, P. Mamone, A. J. Culshaw and M. F. Greaney, Chem. Commun., 2008, 1241 DOI: 10.1039/B719466H

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