Synthesis, structures, and properties of nine-, twelve-, and eighteen-membered N-benzyloxyethyl cyclic α-peptoids

N. Maulucci; I. Izzo; G. Bifulco; A. Aliberti; C. De Cola; D. Comegna; C. Gaeta; A. Napolitano; C. Pizza; C. Tedesco; D. Flot; F. De Riccardis

doi:10.1039/B806508J

Synthesis, structures, and properties of nine-, twelve-, and eighteen-membered N-benzyloxyethyl cyclic α-peptoids†

N. Maulucci,^a I. Izzo,*^a G. Bifulco,^b A. Aliberti,^a C. De Cola,^a D. Comegna,^a C. Gaeta,^a A. Napolitano,^b C. Pizza,^b C. Tedesco,^a D. Flot^c and F. De Riccardis*^a

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^a Department of Chemistry, University of Salerno, Via Ponte Don Melillo, Salerno, Italy
E-mail: dericca@unisa.it, iizzo@unisa.it
Fax: +39 089 969603
Tel: +39 089 969552

^b Department of Pharmaceutical Sciences, University of Salerno, Via Ponte Don Melillo, Salerno, Italy

^c EMBL, 6 rue J. Horowitz, BP 181, France

Abstract

N-Benzyloxyethyl cyclic α-peptoids of various size were prepared and their conformational features were investigated by means of computational, spectroscopic, and X-ray crystallographic studies.

Chemical Communications

Synthesis, structures, and properties of nine-, twelve-, and eighteen-membered N-benzyloxyethyl cyclic α-peptoids†

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Synthesis, structures, and properties of nine-, twelve-, and eighteen-membered N-benzyloxyethyl cyclic α-peptoids

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