Issue 41, 2008

Configurational assignment of rhizopodin, an actin-binding macrolide from the myxobacterium Myxococcus stipitatus

Abstract

The relative and absolute stereochemistry of the 38-membered myxobacterial polyketiderhizopodin, a potent actin-binding macrolide, was determined by J-based configurational analysis in combination with molecular modeling and chemical derivatization.

Graphical abstract: Configurational assignment of rhizopodin, an actin-binding macrolide from the myxobacterium Myxococcus stipitatus

Supplementary files

Article information

Article type
Communication
Submitted
18 Jun 2008
Accepted
24 Jul 2008
First published
09 Sep 2008

Chem. Commun., 2008, 5173-5175

Configurational assignment of rhizopodin, an actin-binding macrolide from the myxobacterium Myxococcus stipitatus

N. Horstmann and D. Menche, Chem. Commun., 2008, 5173 DOI: 10.1039/B810405K

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