Issue 48, 2008
From the journal:

Chemical Communications

Amplified fluorescence determination of microRNAs in homogeneous solution with cationic conjugated polymers†

Yali Zhang,ab   Zhengping Li*a  and  Yongqiang Chenga  

* Corresponding authors

a Key Laboratory of Medicine Chemistry and Molecular Diagnosis, Ministry of Education, College of Chemistry and Environmental Science, Hebei University, Baoding, Hebei Province, PR China
E-mail: lzpbd@hbu.edu.cn
Fax: +86 312 5079403

b College of Sciences, Hebei University of Science and Technology, Shijiazhuang, Hebei Province, PR China

Abstract

Combining the miRNA-primed extension reaction and the optical amplification of a conjugated polymer, a sensitive, selective and homogeneous method for miRNA determination has been developed based on a fluorescence resonance energy transfer (FRET) mechanism.

Graphical abstract: Amplified fluorescence determination of microRNAs in homogeneous solution with cationic conjugated polymers

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Article information

DOI
https://doi.org/10.1039/B816614E
Article type
Communication
Submitted
22 Sep 2008
Accepted
15 Oct 2008
First published
13 Nov 2008

Chem. Commun., 2008, 6579-6581

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Amplified fluorescence determination of microRNAs in homogeneous solution with cationic conjugated polymers

Y. Zhang, Z. Li and Y. Cheng, Chem. Commun., 2008, 6579 DOI: 10.1039/B816614E

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