Issue 14, 2009

Photoresponsive tandem zinc finger peptide

Abstract

A photoresponsive tandem zinc finger peptide has been synthesized by attaching an azobenzene unit at its N-terminus resulting in a conjugate that retained a high binding ability toward the target DNA sequence, whereas it showed a significant decrease in DNA-binding ability after photoisomerization by UV irradiation to switch off the inhibition function from the DNA-binding protein.

Graphical abstract: Photoresponsive tandem zinc finger peptide

Supplementary files

Article information

Article type
Communication
Submitted
06 Nov 2008
Accepted
03 Feb 2009
First published
20 Feb 2009

Chem. Commun., 2009, 1906-1908

Photoresponsive tandem zinc finger peptide

A. Nomura and A. Okamoto, Chem. Commun., 2009, 1906 DOI: 10.1039/B819838A

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