Issue 21, 2009
From the journal:

Chemical Communications

Chemically-selective surface glyco-functionalization of liposomes through Staudinger ligation†

Hailong Zhang,a   Yong Maa  and  Xue-Long Sun*a  

* Corresponding authors

a Department of Chemistry, Cleveland State University, 2121 Euclid Ave, Cleveland, USA
E-mail: x.sun55@csuohio.edu
Fax: +1 216-687-9289
Tel: +1 216-687-3919

Abstract

An efficient and chemoselective liposome surface glyco-functionalization method has been developed based on Staudinger ligation, in which the carbohydrate derivative carrying an azide spacer is conjugated onto the surface of preformed liposomes bearing a terminal triphosphine in PBSbuffer (pH 7.4) at room temperature.

Graphical abstract: Chemically-selective surface glyco-functionalization of liposomes through Staudinger ligation

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Article information

DOI
https://doi.org/10.1039/B822420J
Article type
Communication
Submitted
15 Dec 2008
Accepted
19 Mar 2009
First published
28 Apr 2009

Chem. Commun., 2009, 3032-3034

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Chemically-selective surface glyco-functionalization of liposomes through Staudinger ligation

H. Zhang, Y. Ma and X. Sun, Chem. Commun., 2009, 3032 DOI: 10.1039/B822420J

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