Issue 17, 2009

Synthesis of 2-fluoroalkylbenzimidazoles via copper(i)-catalyzed tandem reactions

Abstract

Preparation of 2-fluoroalkylbenzimidazoles from N-aryl trifluoroacetimidoyl (or bromodifluoroacetimidoyl) chlorides and primary amines has been achieved via copper(I)-catalyzed tandem reactions.

Graphical abstract: Synthesis of 2-fluoroalkylbenzimidazoles via copper(i)-catalyzed tandem reactions

Supplementary files

Article information

Article type
Communication
Submitted
16 Jan 2009
Accepted
12 Feb 2009
First published
09 Mar 2009

Chem. Commun., 2009, 2338-2340

Synthesis of 2-fluoroalkylbenzimidazoles via copper(I)-catalyzed tandem reactions

J. Zhu, H. Xie, Z. Chen, S. Li and Y. Wu, Chem. Commun., 2009, 2338 DOI: 10.1039/B900984A

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