Issue 37, 2009
From the journal:

Chemical Communications

A mass spectrometric investigation of the ability of metal complexes to modulate transcription factor activity†

Jihan Talib,a   Jennifer L. Beck,a   Thitima Urathamakul,a   Cuong D. Nguyen,b   Janice R. Aldrich-Wright,c   Joel P. Mackayb  and  Stephen F. Ralph*a  

* Corresponding authors

a School of Chemistry, University of Wollongong, Wollongong, Australia
E-mail: sralph@uow.edu.au
Fax: +61 2 4221 4287
Tel: +61 2 4221 4286

b School of Molecular and Microbial Biosciences, University of Sydney, Sydney, Australia

c School of Biomedical and Health Sciences, University of Western Sydney, Locked Bag 1797, Penrith South DC, Australia

Abstract

ESI mass spectrometry was used to assess the ability of metal complexes to inhibit binding of a transcription factor to a DNA molecule containing its recognition sequence.

Graphical abstract: A mass spectrometric investigation of the ability of metal complexes to modulate transcription factor activity

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Article information

DOI
https://doi.org/10.1039/B904751D
Article type
Communication
Submitted
09 Mar 2009
Accepted
14 Jul 2009
First published
05 Aug 2009

Chem. Commun., 2009, 5546-5548

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A mass spectrometric investigation of the ability of metal complexes to modulate transcription factor activity

J. Talib, J. L. Beck, T. Urathamakul, C. D. Nguyen, J. R. Aldrich-Wright, J. P. Mackay and S. F. Ralph, Chem. Commun., 2009, 5546 DOI: 10.1039/B904751D

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