Issue 36, 2009
From the journal:

Chemical Communications

A novel iodine-mediated tandem cyclization–cycloaddition reaction leading to polyoxacyclic ring systems†

Yong-Xin Xie,a   Ze-Yi Yan,b   Bo Qian,a   Wen-Ye Deng,c   Dan-Zhu Wang,a   Lu-Yong Wu,a   Xue-Yuan Liua  and  Yong-Min Liang*a  

* Corresponding authors

a State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, P. R. China
E-mail: liangym@lzu.edu.cn
Fax: 0086-931-8912582

b Laboratory of Radiochemistry, School of Nuclear Science and Technology, Lanzhou University, Lanzhou 730000, P. R. China

c China Academy of Engineering Physics, P. O. Box 919 (516), Mianyang 621900, China

Abstract

A novel iodine-catalyzed tandem cyclization–cycloaddition reaction of ortho-alkynyl-substituted benzaldehydes leading to polyoxacyclic ring systems has been developed, which represents a useful approach towards the synthesis of the oxabicyclo-[3.2.1]octane ring skeleton found in a variety of natural products.

Graphical abstract: A novel iodine-mediated tandem cyclization–cycloaddition reaction leading to polyoxacyclic ring systems

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Article information

DOI
https://doi.org/10.1039/B910232A
Article type
Communication
Submitted
26 May 2009
Accepted
03 Jul 2009
First published
30 Jul 2009

Chem. Commun., 2009, 5451-5453

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A novel iodine-mediated tandem cyclization–cycloaddition reaction leading to polyoxacyclic ring systems

Y. Xie, Z. Yan, B. Qian, W. Deng, D. Wang, L. Wu, X. Liu and Y. Liang, Chem. Commun., 2009, 5451 DOI: 10.1039/B910232A

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