Issue 36, 2009
From the journal:

Chemical Communications

pH-Responsive mechanised nanoparticles gated by semirotaxanes†

Niveen M. Khashab,‡a   Matthew E. Belowich,a   Ali Trabolsi,‡a   Douglas C. Friedman,a   Cory Valente,a   Yuen Lau,b   Hussam A. Khatib,a   Jeffrey I. Zink*b  and  J. Fraser Stoddart*a  

* Corresponding authors

a Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, USA
E-mail: stoddart@northwestern.edu
Fax: +1 847-491-1009
Tel: +1 847-491-3793

b Department of Chemistry and Biochemistry, University of California Los Angelos (UCLA), 607 Charles E. Young Drive East, Los Angeles, USA
E-mail: zink@chem.ucla.edu
Fax: +1 310-206-4038
Tel: +1 310-825-1001

Abstract

A [2]pseudorotaxane-based mechanised nanoparticle system, which operates within an aqueous acidic environment, has been prepared and characterised; this integrated system affords both water-soluble stalk and ring components in an effort to improve the biocompatibility of these promising new drug delivery vehicles.

Graphical abstract: pH-Responsive mechanised nanoparticles gated by semirotaxanes

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Article information

DOI
https://doi.org/10.1039/B910431C
Article type
Communication
Submitted
27 May 2009
Accepted
23 Jul 2009
First published
18 Aug 2009

Chem. Commun., 2009, 5371-5373

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pH-Responsive mechanised nanoparticles gated by semirotaxanes

N. M. Khashab, M. E. Belowich, A. Trabolsi, D. C. Friedman, C. Valente, Y. Lau, H. A. Khatib, J. I. Zink and J. F. Stoddart, Chem. Commun., 2009, 5371 DOI: 10.1039/B910431C

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