Issue 42, 2009
From the journal:

Chemical Communications

Direct chemoselective synthesis of glyconanoparticles from unprotected reducing glycans and glycopeptide aldehydes†

Mikkel B. Thygesen,a   Kasper K. Sørensen,a   Emiliano Clóa  and  Knud J. Jensen*a  

* Corresponding authors

a IGM-Bioorganic Chemistry, Centre for Carbohydrate Recognition and Signalling, Faculty of Life Sciences, University of Copenhagen, Thorvaldsensvej 40, DK-1871 Frederiksberg C, Denmark
E-mail: kjj@life.ku.dk
Fax: +45 3533 2398
Tel: +45 3533 2430

Abstract

Chemoselective oxime coupling was used for facile conjugation of unprotected, reducing glycans and glycopeptide aldehydes with core–shell gold nanoparticles carrying reactive aminooxy groups on the organic shell.

Graphical abstract: Direct chemoselective synthesis of glyconanoparticles from unprotected reducing glycans and glycopeptide aldehydes

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Article information

DOI
https://doi.org/10.1039/B911676A
Article type
Communication
Submitted
16 Jun 2009
Accepted
21 Sep 2009
First published
01 Oct 2009

Chem. Commun., 2009, 6367-6369

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Direct chemoselective synthesis of glyconanoparticles from unprotected reducing glycans and glycopeptide aldehydes

M. B. Thygesen, K. K. Sørensen, E. Cló and K. J. Jensen, Chem. Commun., 2009, 6367 DOI: 10.1039/B911676A

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