Issue 45, 2009

In situ, real-time tracking of cell wall topography and nanomechanics of antimycobacterial drugs treated Mycobacterium JLS using atomic force microscopy

Abstract

Two antimycobacterial drugs ethambutol (EMB) and isoniazid (INH) were found to result in decreases of biomechanical properties including adhesion force, cell wall spring constant, and Young’s modulus in Mycobacterium sp. strain JLS (M. JLS).

Graphical abstract: In situ, real-time tracking of cell wall topography and nanomechanics of antimycobacterial drugs treated Mycobacterium JLS using atomic force microscopy

Supplementary files

Article information

Article type
Communication
Submitted
20 Jul 2009
Accepted
21 Sep 2009
First published
09 Oct 2009

Chem. Commun., 2009, 7021-7023

In situ, real-time tracking of cell wall topography and nanomechanics of antimycobacterial drugs treated Mycobacterium JLS using atomic force microscopy

Y. Wu and A. Zhou, Chem. Commun., 2009, 7021 DOI: 10.1039/B914605A

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