Issue 45, 2009
From the journal:

Chemical Communications

Development of 2,6-carboxy-substituted boron dipyrromethene (BODIPY) as a novel scaffold of ratiometric fluorescent probes for live cell imaging†

Toru Komatsu,ac   Yasuteru Urano,a   Yuuta Fujikawa,ac   Tomonori Kobayashi,ac   Hirotatsu Kojima,b   Takuya Terai,a   Kenjiro Hanaokaa  and  Tetsuo Nagano*abc  

* Corresponding authors

a Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan
E-mail: tlong@mol.f.u-tokyo.ac.jp
Fax: +81-3-5841-4855
Tel: +81-3-5841-4850

b Chemical Biology Research Initiative, The University of Tokyo, Japan

c CREST, Japan Science and Technology Agency, Japan

Abstract

Ratiometric fluorescent probes based on boron dipyrromethene (BODIPY) were developed based on a novel design strategy, in which a change of the electron-withdrawing character of the 2,6-substituents resulting from reaction with a target molecule generates a fluorescence wavelength change.

Graphical abstract: Development of 2,6-carboxy-substituted boron dipyrromethene (BODIPY) as a novel scaffold of ratiometric fluorescent probes for live cell imaging

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Article information

DOI
https://doi.org/10.1039/B917209B
Article type
Communication
Submitted
20 Aug 2009
Accepted
22 Sep 2009
First published
08 Oct 2009

Chem. Commun., 2009, 7015-7017

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Development of 2,6-carboxy-substituted boron dipyrromethene (BODIPY) as a novel scaffold of ratiometric fluorescent probes for live cell imaging

T. Komatsu, Y. Urano, Y. Fujikawa, T. Kobayashi, H. Kojima, T. Terai, K. Hanaoka and T. Nagano, Chem. Commun., 2009, 7015 DOI: 10.1039/B917209B

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