Issue 5, 2009
From the journal:

Organic & Biomolecular Chemistry

Synthesis of the pyrrolo[2,3-c]carbazole core of the dictyodendrins†‡

Carles Ayats,*a   Roger Soley,a   Fernando Albericioab  and  Mercedes Álvarez*ac  

* Corresponding authors

a Institute for Research in Biomedicine, Barcelona Scientific Park-University of Barcelona, Baldiri Reixach 10–12, Spain

b Department of Organic Chemistry, University of Barcelona, Spain

c Laboratory of Organic Chemistry, Faculty of Pharmacy, University of Barcelona, Spain
E-mail: mercedes.alvarez@irbbarcelona.org
Fax: (+34) 934037126
Tel: (+34) 934037086

Abstract

The pyrrolo[2,3-c]carbazole 1, the common core of the marine alkaloids known as the dictyodendrins, has been synthesised. The sequence is based on a Suzuki cross-coupling reaction between the pyrrole fragment 2 and the indole fragment 3, followed by tandem photochemical 6π-electrocyclisation/aromatisation.

Graphical abstract: Synthesis of the pyrrolo[2,3-c]carbazole core of the dictyodendrins

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Article information

DOI
https://doi.org/10.1039/B822933N
Article type
Communication
Submitted
19 Dec 2008
Accepted
19 Dec 2008
First published
13 Jan 2009

Org. Biomol. Chem., 2009,7, 860-862

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Synthesis of the pyrrolo[2,3-c]carbazole core of the dictyodendrins

C. Ayats, R. Soley, F. Albericio and M. Álvarez, Org. Biomol. Chem., 2009, 7, 860 DOI: 10.1039/B822933N

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