One-pot tandem 1,4–1,2-addition of phosphites to quinolines†
Abstract
Trialkyl and silylated dialkyl phosphites were evaluated as phosphorus nucleophiles for the addition to quinolines in a strong acidic medium allowing consecutive 1,4- and
* Corresponding authors
a
Research Group SynBioC, Department of Organic Chemistry, Faculty of BioScience Engineering, Coupure Links 653, B-9000 Ghent, Belgium
E-mail:
chris.stevens@ugent.be
Fax: +32 9264 6243
Tel: +32 9264 5950
b
Institute of Chemistry and Environmental Protection, Jan Długosz University, Armii Krajowej 13/15 Ave, 42-201 Czestochowa, Poland
E-mail:
crystal@cz.onet.pl
Fax: +48 34366 5322
Tel: +48 34366 5322
c
Center of Molecular and Macromolecular Studies, Department of Heteroatom Chemistry, Polish Academy of Science, Sienkiewicza 112, 90-363 Lødz, Poland
E-mail:
draj@bilbo.cbmm.lodz.pl
Fax: +48 42684 7126
Tel: +48 42680 3234
Trialkyl and silylated dialkyl phosphites were evaluated as phosphorus nucleophiles for the addition to quinolines in a strong acidic medium allowing consecutive 1,4- and
A. De Blieck, K. G. R. Masschelein, F. Dhaene, E. Rozycka-Sokolowska, B. Marciniak, J. Drabowicz and C. V. Stevens, Chem. Commun., 2010, 46, 258 DOI: 10.1039/B906808B
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