Issue 2, 2010
From the journal:

Chemical Communications

Increasing the hydrophobicity and electrospray response of glycans through derivatization with novel cationic hydrazides†

Michael S. Bereman,a   Daniel L. Cominsa  and  David C. Muddiman*a  

* Corresponding authors

a W.M. Keck FTICR Mass Spectrometry Laboratory, Department of Chemistry, North Carolina State University Raleigh, USA
E-mail: David_Muddiman@ncsu.edu
Tel: +1 919 513 0084

Abstract

Novel tags are used to increase the hydrophobicity of glycans and impart a permanent charge yielding as great as a ∼5-fold increase in electrospray response from both a standard and complex mixture.

Graphical abstract: Increasing the hydrophobicity and electrospray response of glycans through derivatization with novel cationic hydrazides

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Article information

DOI
https://doi.org/10.1039/B915589A
Article type
Communication
Submitted
30 Jul 2009
Accepted
04 Nov 2009
First published
17 Nov 2009

Chem. Commun., 2010,46, 237-239

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Increasing the hydrophobicity and electrospray response of glycans through derivatization with novel cationic hydrazides

M. S. Bereman, D. L. Comins and D. C. Muddiman, Chem. Commun., 2010, 46, 237 DOI: 10.1039/B915589A

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