Issue 5, 2010
From the journal:

Chemical Communications

Galactosylated cucurbituril-inclusion polyplex for hepatocyte-targeted gene delivery†

Soo Kyung Kim,a   Kyeng Min Park,b   Kaushik Singha,a   Jeeyeon Kim,b   Youngjoo Ahn,b   Kimoon Kim*b  and  Won Jong Kim*a  

* Corresponding authors

a Department of Chemistry, BK21 Program, Polymer Research Institute, Pohang University of Science and Technology (POSTECH), Pohang 790-784, Korea
E-mail: wjkim@postech.ac.kr
Fax: +82-54-279-3399
Tel: +82-54-279-2104

b National Creative Research Initiative Center for Smart Supramolecules (CSS), Department of Chemistry and Division of Advanced Materials Science, Pohang University of Science and Technology (POSTECH), Pohang 790-784, Korea
E-mail: kkim@postech.ac.kr
Fax: +82-54-279-8129
Tel: +82-54-279-2113

Abstract

The work demonstrates a judicious approach to achieve hepatocyte cell-targeted highly efficient gene delivery by utilizing a supramolecular complex of galactosylated cucurbituril and dextran–spermine conjugates.

Graphical abstract: Galactosylated cucurbituril-inclusion polyplex for hepatocyte-targeted gene delivery

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Article information

DOI
https://doi.org/10.1039/B920753H
Article type
Communication
Submitted
07 Oct 2009
Accepted
27 Nov 2009
First published
16 Dec 2009

Chem. Commun., 2010,46, 692-694

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Galactosylated cucurbituril-inclusion polyplex for hepatocyte-targeted gene delivery

S. K. Kim, K. M. Park, K. Singha, J. Kim, Y. Ahn, K. Kim and W. J. Kim, Chem. Commun., 2010, 46, 692 DOI: 10.1039/B920753H

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