Issue 1, 2010
From the journal:

Chemical Communications

Total synthesis of largamide H†

Shuo Liang,a   Zhengshuang Xu*ab  and  Tao Ye*ab  

* Corresponding authors

a Laboratory of Chemical Genomics, Peking University Shenzhen Graduate School, University Town of Shenzhen, Xili, Nanshan District, Shenzhen, China
E-mail: yet@szpku.edu.cn, xuzs@szpku.edu.cn
Tel: +86 755 26032697

b Department of Applied Biology & Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China
E-mail: bctaoye@inet.polyu.edu.hk
Fax: +852 22641912
Tel: +852 34008722

Abstract

Total synthesis of largamide H has been completed, utilising the oxidative elimination reaction of enantiomerically pure 2-amino-3-(phenylselenyl)butanoic acid residues to stereospecifically install both (Z)- and (E)-2,3-dehydro-2-aminobutanoic moieties.

Graphical abstract: Total synthesis of largamide H

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Article information

DOI
https://doi.org/10.1039/B921000H
Article type
Communication
Submitted
07 Oct 2009
Accepted
29 Oct 2009
First published
16 Nov 2009

Chem. Commun., 2010,46, 153-155

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Total synthesis of largamide H

S. Liang, Z. Xu and T. Ye, Chem. Commun., 2010, 46, 153 DOI: 10.1039/B921000H

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