Issue 5, 2010
From the journal:

Chemical Communications

Combinatorial synthesis of a triphenylmethine library and their application in the development of Surface Enhanced Raman Scattering (SERS) probes†

Sung Ju Cho,a   Young-Hoon Ahn,‡b   Kaustabh Kumar Maiti,a   U. S. Dinish,a   Chit Yaw Fu,a   Praveen Thoniyot,a   Malini Olivo*acd  and  Young-Tae Chang*ae  

* Corresponding authors

a Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, Singapore 138667
E-mail: chmcyt@nus.edu.sg
Fax: +65 6478 9957
Tel: +65 6478 8761

b Department of Chemistry, New York University, New York, USA

c National Cancer Center, 11 Hospital Drive, Singapore 169610

d School of Physics, National University Ireland, Galway, Ireland

e Department of Chemistry, National University of Singapore, Singapore 11754

Abstract

The first synthesis of a triphenylmethine (TM) library of compounds and screening of their Surface Enhanced Raman Scattering (SERS) capability was carried out to identify novel Raman reporters with high sensitivity. We identified three novel SERS reporters (B2, B7, and C7) with higher signal intensity than that of commonly used crystal violet (CV). These reporters may find potential applications in developing sensitive SERS based biosensors.

Graphical abstract: Combinatorial synthesis of a triphenylmethine library and their application in the development of Surface Enhanced Raman Scattering (SERS) probes

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Article information

DOI
https://doi.org/10.1039/B921550F
Article type
Communication
Submitted
14 Oct 2009
Accepted
26 Nov 2009
First published
17 Dec 2009

Chem. Commun., 2010,46, 722-724

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Combinatorial synthesis of a triphenylmethine library and their application in the development of Surface Enhanced Raman Scattering (SERS) probes

S. J. Cho, Y. Ahn, K. K. Maiti, U. S. Dinish, C. Y. Fu, P. Thoniyot, M. Olivo and Y. Chang, Chem. Commun., 2010, 46, 722 DOI: 10.1039/B921550F

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