Issue 12, 2010
From the journal:

Chemical Communications

Photoinduced DNA damage efficiency and cytotoxicity of novel viologen linked pyrene conjugates†

Mahesh Hariharan,a   Suneesh C. Karunakaran,a   Danaboyina Ramaiah,*a   Ina Schulzb  and  Bernd Epeb  

* Corresponding authors

a Photosciences & Photonics, National Institute for Interdisciplinary Science & Technology, CSIR, Trivandrum 695 019, India
E-mail: rama@niist.res.in, d_ramaiah@rediffmail.com
Fax: (+91)-471-2490186

b Institute of Pharmacy, University of Mainz, D-55099 Mainz, Germany
E-mail: epe@uni-mainz.de
Fax: (+49)-6131-39255321

Abstract

Novel viologen linked pyrene conjugates permeate cells efficiently and exhibit spacer length dependent DNA damage and cytotoxicity upon photoexcitation.

Graphical abstract: Photoinduced DNA damage efficiency and cytotoxicity of novel viologen linked pyrene conjugates

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Article information

DOI
https://doi.org/10.1039/B924943E
Article type
Communication
Submitted
26 Nov 2009
Accepted
28 Jan 2010
First published
18 Feb 2010

Chem. Commun., 2010,46, 2064-2066

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Photoinduced DNA damage efficiency and cytotoxicity of novel viologen linked pyrene conjugates

M. Hariharan, S. C. Karunakaran, D. Ramaiah, I. Schulz and B. Epe, Chem. Commun., 2010, 46, 2064 DOI: 10.1039/B924943E

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