Issue 23, 2010

Assembly of dsDNA nanocircles into dimeric and oligomeric aggregates

Abstract

The assembly of double-stranded (ds) DNA nanocircles both by hybridization with branched oligodeoxynucleotides (ODNs) and by intercalation was analyzed by atomic force microscopy (AFM). Branched ODNs ligated to single-stranded (ss) gap regions of dsDNA nanocircles led to defined, dumbbell-shaped architectures. ODNs containing an aromatic intercalator yielded oligomeric aggregates.

Graphical abstract: Assembly of dsDNA nanocircles into dimeric and oligomeric aggregates

Supplementary files

Article information

Article type
Communication
Submitted
15 Mar 2010
Accepted
29 Apr 2010
First published
17 May 2010

Chem. Commun., 2010,46, 4154-4156

Assembly of dsDNA nanocircles into dimeric and oligomeric aggregates

D. Ackermann, G. Rasched, S. Verma, T. L. Schmidt, A. Heckel and M. Famulok, Chem. Commun., 2010, 46, 4154 DOI: 10.1039/C0CC00390E

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