Issue 36, 2010

HSA coated MnOnanoparticles with prominent MRI contrast for tumor imaging

Abstract

We report in this Communication a facile, two-step surface modification strategy to achieve manganese oxide nanoparticles with prominent MRI T1 contrast. In a U87MG glioblastoma xenograft model, we confirmed that the particles can accumulate efficiently in tumor area to induce effective T1 signal alteration.

Graphical abstract: HSA coated MnO nanoparticles with prominent MRI contrast for tumor imaging

Supplementary files

Article information

Article type
Communication
Submitted
21 Apr 2010
Accepted
12 Jul 2010
First published
23 Aug 2010

Chem. Commun., 2010,46, 6684-6686

HSA coated MnO nanoparticles with prominent MRI contrast for tumor imaging

J. Huang, J. Xie, K. Chen, L. Bu, S. Lee, Z. Cheng, X. Li and X. Chen, Chem. Commun., 2010, 46, 6684 DOI: 10.1039/C0CC01041C

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