Issue 36, 2010
From the journal:

Chemical Communications

Motif-programmed artificial proteins mediated nucleation of octacalcium phosphate on titanium substrates†

Toru Tsuji,ab   Yuya Oaki,a   Masao Yoshinari,c   Takashi Katoa  and  Kiyotaka Shiba*b  

* Corresponding authors

a Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo, Japan
E-mail: kato@chiral.t.u-tokyo.ac.jp
Fax: +81 3-5841-8661
Tel: +81 3-5841-7440

b Division of Protein Engineering, Cancer Institute, Japanese Foundation for Cancer Research, Koto, Tokyo, Japan
E-mail: kshiba@jfcr.or.jp
Fax: +81 3-3570 0461
Tel: +81 3-3570 0489

c Division of Oral Implants Research, Oral Health Science Center, Tokyo Dental College, 1-2-2, Masago, Mihama-ku, Chiba, Japan

Abstract

We report the creation of motif-based artificial proteins that bind to titanium surfaces and mediate the deposition of crystalline calcium phosphate. These proteins enabled in aqua surface modification of titanium materials having an intricate structure used in medical applications.

Graphical abstract: Motif-programmed artificial proteins mediated nucleation of octacalcium phosphate on titanium substrates

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Article information

DOI
https://doi.org/10.1039/C0CC01512A
Article type
Communication
Submitted
21 May 2010
Accepted
26 Jul 2010
First published
18 Aug 2010

Chem. Commun., 2010,46, 6675-6677

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Motif-programmed artificial proteins mediated nucleation of octacalcium phosphate on titanium substrates

T. Tsuji, Y. Oaki, M. Yoshinari, T. Kato and K. Shiba, Chem. Commun., 2010, 46, 6675 DOI: 10.1039/C0CC01512A

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