Issue 40, 2010

Metal-free deprotonative functionalization of heteroaromatics using organic superbase catalyst

Abstract

Metal-free deprotonative functionalization of heteroaromatic compounds was achieved using an organic superbase catalyst; an organosilicon additive such as trimethylsilylpropyne was employed for activating the catalytic cycle of 1,2-addition to carbonyl compounds.

Graphical abstract: Metal-free deprotonative functionalization of heteroaromatics using organic superbase catalyst

Supplementary files

Article information

Article type
Communication
Submitted
07 Aug 2010
Accepted
01 Sep 2010
First published
17 Sep 2010

Chem. Commun., 2010,46, 7623-7624

Metal-free deprotonative functionalization of heteroaromatics using organic superbase catalyst

Y. Hirono, K. Kobayashi, M. Yonemoto and Y. Kondo, Chem. Commun., 2010, 46, 7623 DOI: 10.1039/C0CC03106B

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