Issue 46, 2010
From the journal:

Chemical Communications

Superquenching acridinium ester chemiluminescence by gold nanoparticles for DNA detection†

Qinfeng Xu,a   Jing Liu,a   Zhike He*a  and  Si Yanga  

* Corresponding authors

a Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, P. R. China
E-mail: zhkhe@whu.edu.cn
Fax: +86-27-6875-4067
Tel: +86-27-6875-6557

Abstract

It was found that the chemiluminescence of acridinium ester (AE) was quenched effectively by gold nanoparticles (AuNPs) with Stern–Volmer constants approaching 1010 M−1, which was exploited to realize sequence-specific DNA detection based on the preferential absorption of AE-tagged single-strand probe on unmodified AuNPs over the hybrids of probe and target DNA.

Graphical abstract: Superquenching acridinium ester chemiluminescence by gold nanoparticles for DNA detection

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Article information

DOI
https://doi.org/10.1039/C0CC03349A
Article type
Communication
Submitted
19 Aug 2010
Accepted
28 Sep 2010
First published
19 Oct 2010

Chem. Commun., 2010,46, 8800-8802

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Superquenching acridinium ester chemiluminescence by gold nanoparticles for DNA detection

Q. Xu, J. Liu, Z. He and S. Yang, Chem. Commun., 2010, 46, 8800 DOI: 10.1039/C0CC03349A

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