Issue 20, 2010
From the journal:

Organic & Biomolecular Chemistry

The organocatalytic two-step synthesis of diversely functionalized tricyclic tetrazoles†‡

Xiong Huang,a   Ping Li,a   Xin-Sheng Li,a   Dong-Cheng Xua  and  Jian-Wu Xie*a  

* Corresponding authors

a Key Laboratory of the Ministry of Education for Advanced Catalysis Materials, Department of Chemistry and Life Science, Zhejiang Normal University, P. R. of China
E-mail: xiejw@zjnu.cn
Fax: +86 579 82282610

Abstract

The diversely functionalized tricyclic tetrazoles were synthesised from readily available substrates via intramolecular 1,3-dipolar cycloaddition as the key step in good yields (53–78% yield for two steps) with high enantioselectivities (81–99% ee).

Graphical abstract: The organocatalytic two-step synthesis of diversely functionalized tricyclic tetrazoles

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Article information

DOI
https://doi.org/10.1039/C0OB00272K
Article type
Communication
Submitted
16 Jun 2010
Accepted
29 Jul 2010
First published
23 Aug 2010

Org. Biomol. Chem., 2010,8, 4527-4529

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The organocatalytic two-step synthesis of diversely functionalized tricyclic tetrazoles

X. Huang, P. Li, X. Li, D. Xu and J. Xie, Org. Biomol. Chem., 2010, 8, 4527 DOI: 10.1039/C0OB00272K

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