Herein, we demonstrate how to detect nucleic acids that do not contain restriction endonuclease recognition sites with restriction endonucleases. We show that the topology of DNA probes used in this detection strategy remarkably affects the efficiency of RNA/DNA detection.
L. Yan, S. Nakayama, S. Yitbarek, I. Greenfield and H. O. Sintim, Chem. Commun., 2011, 47, 200 DOI: 10.1039/C0CC02208J
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