Issue 2, 2011
From the journal:

Chemical Communications

Biocompatible functionalisation of starch†‡

Apostolos Alissandratos,a   Nina Baudendistel,b   Bernhard Hauer,b   Kai Baldenius,b   Sabine Flitschc  and  Peter Halling*a  

* Corresponding authors

a WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, Thomas Graham Building, 295 Cathedral Street, Glasgow, UK
E-mail: p.j.halling@strath.ac.uk
Fax: +44 (0)141 548 4822
Tel: +44 (0)141 548 2683

b BASF-AG, Fine Chemicals and Biocatalysis Research, Ludwigshafen, Germany

c School of Chemistry, Manchester Interdisciplinary Biocentre, 131 Princess Street, Manchester, UK

Abstract

The enzyme catalysed esterification of starch and fatty acids with terminal triple bonds is described. This material can be used as an acceptor for azide containing molecules, through azide/alkyne cycloaddition. The potential is illustrated by the production of fluorescently-labelled starch, and a biotinylated derivative which can bind streptavidin.

Graphical abstract: Biocompatible functionalisation of starch

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Article information

DOI
https://doi.org/10.1039/C0CC02908D
Article type
Communication
Submitted
30 Jul 2010
Accepted
27 Oct 2010
First published
22 Nov 2010

Chem. Commun., 2011,47, 683-685

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Biocompatible functionalisation of starch

A. Alissandratos, N. Baudendistel, B. Hauer, K. Baldenius, S. Flitsch and P. Halling, Chem. Commun., 2011, 47, 683 DOI: 10.1039/C0CC02908D

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