Issue 6, 2011
From the journal:

Chemical Communications

Efficient and general synthesis of oxazino[4,3-a]indoles by cascade addition-cyclization reactions of (1H-indol-2-yl)methanols and vinyl sulfonium salts†

Jing An,a   Ning-Jie Chang,a   Li-Dong Song,a   Yu-Qin Jin,a   Ying Ma,a   Jia-Rong Chen*a  and  Wen-Jing Xiao*a  

* Corresponding authors

a Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, 152 Luoyu Road, Wuhan, Hubei 430079, China
E-mail: wxiao@mail.ccnu.edu.cn
Fax: +86 27 67862041
Tel: +86 27 67862041

Abstract

An efficient and general approach to oxazino[4,3-a]indole architectures is described. The addition-cyclization cascade of (1H-indol-2-yl)methanols with vinyl sulfonium salts affords oxazino[4,3-a]indole derivatives in high yields.

Graphical abstract: Efficient and general synthesis of oxazino[4,3-a]indoles by cascade addition-cyclization reactions of (1H-indol-2-yl)methanols and vinyl sulfonium salts

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Article information

DOI
https://doi.org/10.1039/C0CC03823G
Article type
Communication
Submitted
13 Sep 2010
Accepted
16 Nov 2010
First published
30 Nov 2010

Chem. Commun., 2011,47, 1869-1871

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Efficient and general synthesis of oxazino[4,3-a]indoles by cascade addition-cyclization reactions of (1H-indol-2-yl)methanols and vinyl sulfonium salts

J. An, N. Chang, L. Song, Y. Jin, Y. Ma, J. Chen and W. Xiao, Chem. Commun., 2011, 47, 1869 DOI: 10.1039/C0CC03823G

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