Issue 5, 2011
From the journal:

Chemical Communications

Multifunctional divalent vancomycin: the fluorescent imaging and photodynamic antimicrobial properties for drug resistant bacteria†

Bengang Xing,*a   Tingting Jiang,a   Wuguo Bi,a   Yanmei Yang,a   Lihua Li,b   Manlun Ma,b   Chi-Kwong Chang,c   Bing Xu*b  and  Edwin Kok Lee Yeow*a  

* Corresponding authors

a Division of Chemistry and Biological Chemistry, School of Physical & Mathematical Sciences, Nanyang Technological University, Singapore
E-mail: Bengang@ntu.edu.sg, Edwinyeow@ntu.edu.sg

b Department of Chemistry, Brandeis University, Waltham, USA
E-mail: bxu@brandeis.edu

c Department of Chemistry, Michigan State University, Eastlansing, USA

Abstract

A simple and specific divalent vancomycin–porphyrin has been developed. This divalent vancomycin–porphyrin conjugate indicates promising properties in fluorescent imaging and photodynamic inactivation of vancomycin-sensitive and vancomycin-resistant enterococci (VRE) bacterial strains.

Graphical abstract: Multifunctional divalent vancomycin: the fluorescent imaging and photodynamic antimicrobial properties for drug resistant bacteria

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Article information

DOI
https://doi.org/10.1039/C0CC04434B
Article type
Communication
Submitted
15 Oct 2010
Accepted
09 Nov 2010
First published
26 Nov 2010

Chem. Commun., 2011,47, 1601-1603

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Multifunctional divalent vancomycin: the fluorescent imaging and photodynamic antimicrobial properties for drug resistant bacteria

B. Xing, T. Jiang, W. Bi, Y. Yang, L. Li, M. Ma, C. Chang, B. Xu and E. K. L. Yeow, Chem. Commun., 2011, 47, 1601 DOI: 10.1039/C0CC04434B

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