Issue 4, 2011
From the journal:

Chemical Communications

The functional valency of dodecamannosylated fullerenes with Escherichia coli FimH—towards novel bacterial antiadhesives†

Maxime Durka,a   Kevin Buffet,a   Julien Iehl,b   Michel Holler,b   Jean-François Nierengarten,*b   Joemar Taganna,c   Julie Bouckaert*c  and  Stéphane P. Vincent*a  

* Corresponding authors

a University of Namur (FUNDP), Département de Chimie, Laboratoire de Chimie Bio-Organique, rue de Bruxelles 61, B-5000 Namur, Belgium
E-mail: stephane.vincent@fundp.ac.be

b Laboratoire de Chimie des Matériaux Moléculaires, Université de Strasbourg et CNRS (UMR 7509), Ecole Européenne de Chimie, Polymères et Matériaux (ECPM), 25 rue Becquerel, 67087 Strasbourg Cedex 2, France
E-mail: nierengarten@chimie.u-strasbg.fr

c Structural Biology Brussels at the Vrije Universiteit Brussel, VIB, Pleinlaan 2, 1050 Brussels, Belgium
E-mail: bouckaej@vub.ac.be

Abstract

Fullerene hexakis-adducts bearing 12 peripheral mannose moieties have been prepared by grafting sugar derivatives onto the fullerene core and assayed as inhibitors of FimH, a bacterial adhesin, using isothermal titration calorimetry, surface plasmon resonance and hemagglutination assays.

Graphical abstract: The functional valency of dodecamannosylated fullerenes with Escherichia coli FimH—towards novel bacterial antiadhesives

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C0CC04468G
Article type
Communication
Submitted
17 Oct 2010
Accepted
28 Oct 2010
First published
22 Nov 2010

Chem. Commun., 2011,47, 1321-1323

Permissions

Request permissions

The functional valency of dodecamannosylated fullerenes with Escherichia coli FimH—towards novel bacterial antiadhesives

M. Durka, K. Buffet, J. Iehl, M. Holler, J. Nierengarten, J. Taganna, J. Bouckaert and S. P. Vincent, Chem. Commun., 2011, 47, 1321 DOI: 10.1039/C0CC04468G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements