Issue 8, 2011
From the journal:

Chemical Communications

Synthesis of DNAblock copolymers with extended nucleic acid segments by enzymatic ligation: cut and paste large hybrid architectures†

Meryem S. Ayaz,‡a   Minseok Kwak,‡b   Fikri E. Alemdaroglu,§b   Jie Wang,a   Rüdiger Bergera  and  Andreas Herrmann*b  

* Corresponding authors

a Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany

b Department of Polymer Chemistry, Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands
E-mail: a.herrmann@rug.nl
Fax: +31 50 363 4400
Tel: +31 50 363 6318

Abstract

Ultra-high molecular weight DNA/polymer hybrid materials were prepared employing molecular biology techniques. Nucleic acid restriction and ligation enzymes were used to generate linear DNA di- and triblock copolymers that contain up to thousands of base pairs in the DNA segments.

Graphical abstract: Synthesis of DNA block copolymers with extended nucleic acid segments by enzymatic ligation: cut and paste large hybrid architectures

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Article information

DOI
https://doi.org/10.1039/C0CC04746E
Article type
Communication
Submitted
02 Nov 2010
Accepted
09 Dec 2010
First published
11 Jan 2011

Chem. Commun., 2011,47, 2243-2245

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Synthesis of DNA block copolymers with extended nucleic acid segments by enzymatic ligation: cut and paste large hybrid architectures

M. S. Ayaz, M. Kwak, F. E. Alemdaroglu, J. Wang, R. Berger and A. Herrmann, Chem. Commun., 2011, 47, 2243 DOI: 10.1039/C0CC04746E

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