Towards energetically viable asymmetric deprotonations: selectivity at more elevated temperatures with C2-symmetric magnesium bisamides

Linsey S. Bennie; William J. Kerr; Michael Middleditch; Allan J. B. Watson

doi:10.1039/C0CC04939E

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Towards energetically viable asymmetric deprotonations: selectivity at more elevated temperatures with C₂-symmetric magnesium bisamides†

Linsey S. Bennie,^a William J. Kerr,*^a Michael Middleditch^a and Allan J. B. Watson^a

Author affiliations

* Corresponding authors

^a Department of Pure and Applied Chemistry, WestCHEM, 295 Cathedral Street, Glasgow, Scotland, UK
E-mail: w.kerr@strath.ac.uk
Fax: +44 (0)141 548 4822
Tel: +44 (0)141 548 2959

Abstract

A novel chiral magnesium bisamide has enabled the development of effective asymmetric deprotonation protocols at substantially more elevated temperatures. This new, structurally simple, C₂-symmetric magnesium complex displays excellent levels of asymmetric efficiency and energy reduction in the synthesis of enantioenriched enol silanes.

Download options Please wait...

Supplementary files

Supplementary information PDF (180K)

Article information

DOI: https://doi.org/10.1039/C0CC04939E
Article type: Communication
Submitted: 12 Nov 2010
Accepted: 22 Dec 2010
First published: 18 Jan 2011

Download Citation

Chem. Commun., 2011,47, 2264-2266

Permissions

Request permissions

Towards energetically viable asymmetric deprotonations: selectivity at more elevated temperatures with C₂-symmetric magnesium bisamides

L. S. Bennie, W. J. Kerr, M. Middleditch and A. J. B. Watson, Chem. Commun., 2011, 47, 2264 DOI: 10.1039/C0CC04939E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Chemical Communications