Issue 11, 2011
From the journal:

Chemical Communications

Bacteria-based AND logic gate: a decision-making and self-powered biosensor

Zhongjian Li,a   Miriam A. Rosenbaum,a   Arvind Venkataraman,a   Tsz Kin Tam,b   Evgeny Katzb  and  Largus T. Angenent*a  

* Corresponding authors

a Department of Biological and Environmental Engineering, Cornell University, 214 Riley-Robb Hall, Ithaca, USA
E-mail: la249@cornell.edu
Fax: +1 607-255-4449
Tel: +1 607-255-2480

b Department of Chemistry and Biomolecular Science, Clarkson University, Potsdam, USA
Fax: +1 315-268-6610
Tel: +1 315-268-4421

Abstract

We developed a bacteria-based AND logic gate using a Pseudomonas aeruginosa lasI/rhlI double mutant with two quorum-sensing signaling molecules as the input signals. We showed a distinct electrical output signal, despite the complexity and continuous regulation of metabolic reactions of living cells.

Graphical abstract: Bacteria-based AND logic gate: a decision-making and self-powered biosensor

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Article information

DOI
https://doi.org/10.1039/C0CC05037G
Article type
Communication
Submitted
18 Nov 2010
Accepted
09 Dec 2010
First published
04 Jan 2011

Chem. Commun., 2011,47, 3060-3062

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Bacteria-based AND logic gate: a decision-making and self-powered biosensor

Z. Li, M. A. Rosenbaum, A. Venkataraman, T. K. Tam, E. Katz and L. T. Angenent, Chem. Commun., 2011, 47, 3060 DOI: 10.1039/C0CC05037G

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