Issue 16, 2011
From the journal:

Chemical Communications

Revealing the nature of thio-click reactions on the solid phase†

M. Talha Gokmen,a   Jérémy Brassinne,a   R. Arun Prasatha  and  Filip E. Du Prez*a  

* Corresponding authors

a Department of Organic Chemistry, Polymer Chemistry Research Group, Ghent University, Krijgslaan 281 S4-bis, B-9000 Ghent, Belgium
E-mail: Filip.DuPrez@UGent.be

Abstract

Thiol- and yne-functionalized beads were manufactured in a simple microfluidic setup. While CuAAC and thiol–yne reactions were performed on yne-functionalized beads, 9 different thiol–X reactions were compared, in terms of kinetics and conversion, on thiol-functionalized beads.

Graphical abstract: Revealing the nature of thio-click reactions on the solid phase

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Article information

DOI
https://doi.org/10.1039/C0CC05340F
Article type
Communication
Submitted
02 Dec 2010
Accepted
04 Mar 2011
First published
21 Mar 2011

Chem. Commun., 2011,47, 4652-4654

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Revealing the nature of thio-click reactions on the solid phase

M. T. Gokmen, J. Brassinne, R. A. Prasath and F. E. Du Prez, Chem. Commun., 2011, 47, 4652 DOI: 10.1039/C0CC05340F

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