Issue 11, 2011
From the journal:

Chemical Communications

A fluorescent molecular ruler as a selective probe for ω-aminoacids†

Daniel Moreno,a   José V. Cuevas,a   Gabriel García-Herbosaa  and  Tomás Torroba*a  

* Corresponding authors

a Departamento de Química, Facultad de Ciencias, Universidad de Burgos, 09001 Burgos, Spain
E-mail: ttorroba@ubu.es
Fax: +34 947258831
Tel: +34 947258088

Abstract

A fluorescent probe for ω-aminoacids behaves as a molecular ruler, changing the yellow fluorescent emission into blue as a function of the distance between the terminal ammonium and the carboxylate groups, permitting the quantitative detection of ω-aminoacids, their metabolites and related drugs, such as pregabalin or gabapentin, from pharmaceutical formulations.

Graphical abstract: A fluorescent molecular ruler as a selective probe for ω-aminoacids

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Article information

DOI
https://doi.org/10.1039/C0CC05454B
Article type
Communication
Submitted
08 Dec 2010
Accepted
17 Jan 2011
First published
31 Jan 2011

Chem. Commun., 2011,47, 3183-3185

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A fluorescent molecular ruler as a selective probe for ω-aminoacids

D. Moreno, J. V. Cuevas, G. García-Herbosa and T. Torroba, Chem. Commun., 2011, 47, 3183 DOI: 10.1039/C0CC05454B

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