Issue 12, 2011
From the journal:

Chemical Communications

Ligand inducible assembly of a DNA tetrahedron†

Chikara Dohno,a   Hiroshi Atsumia  and  Kazuhiko Nakatani*a  

* Corresponding authors

a Department of Regulatory Bioorganic Chemistry, The Institute of Scientific and Industrial Research (ISIR), Osaka University, Ibaraki 567-0047, Japan
E-mail: nakatani@sanken.osaka-u.ac.jp
Fax: +81 6 6879 8459
Tel: +81 6 6879 8455

Abstract

Here we show that a small synthetic ligand can be used as a key building component for DNA nanofabrication. Using naphthyridinecarbamate dimer (NCD) as a molecular glue for DNA hybridization, we demonstrate NCD-triggered formation of a DNA tetrahedron.

Graphical abstract: Ligand inducible assembly of a DNA tetrahedron

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Article information

DOI
https://doi.org/10.1039/C0CC05473A
Article type
Communication
Submitted
09 Dec 2010
Accepted
21 Jan 2011
First published
07 Feb 2011

Chem. Commun., 2011,47, 3499-3501

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Ligand inducible assembly of a DNA tetrahedron

C. Dohno, H. Atsumi and K. Nakatani, Chem. Commun., 2011, 47, 3499 DOI: 10.1039/C0CC05473A

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