Issue 15, 2011
From the journal:

Chemical Communications

Ionic catch and release oligosaccharide synthesis (ICROS)†

Anh-Tuan Tran,a   Richard Burden,a   Daugirdas T. Racysa  and  M. Carmen Galan*a  

* Corresponding authors

a School of Chemistry, University of Bristol, Cantock's Close, Bristol, UK
E-mail: M.C.Galan@bristol.ac.uk
Fax: +44 (0)1179298611
Tel: +44 (0)1179287654

Abstract

A general and efficient chromatography-free ionic-liquid-supported “catch-and-release” strategy for oligosaccharide synthesis (ICROS) is reported. The methodology is compatible with current glycosylation strategies and amenable to protecting group manipulations. A series of β-(1→6) and β-(1→2)-linked glycan structures have been prepared to showcase the versatility of the strategy.

Graphical abstract: Ionic catch and release oligosaccharide synthesis (ICROS)

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Article information

DOI
https://doi.org/10.1039/C0CC05580H
Article type
Communication
Submitted
14 Dec 2010
Accepted
22 Feb 2011
First published
09 Mar 2011

Chem. Commun., 2011,47, 4526-4528

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Ionic catch and release oligosaccharide synthesis (ICROS)

A. Tran, R. Burden, D. T. Racys and M. Carmen Galan, Chem. Commun., 2011, 47, 4526 DOI: 10.1039/C0CC05580H

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