Issue 16, 2011
From the journal:

Chemical Communications

An aptamer-based signal-on and multiplexed sensing platform for one-spot simultaneous electronic detection of proteins and small molecules†

Yun Xiang,*a   Xiaoqing Qian,a   Bingying Jiang,b   Yaqin Chaia  and  Ruo Yuan*a  

* Corresponding authors

a Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China
E-mail: yunatswu@swu.edu.cn, yuanruo@swu.edu.cn
Fax: +86-23-68252277
Tel: +86-23-68253172

b School of Chemistry and Chemical Engineering, Chongqing University of Technology, Chongqing 400040, P. R. China

Abstract

One-spot signal-on and simultaneous electronic detection of lysozyme and adenosine is achieved based on target-induced release of aptamers and back-filling hybridization of the resulting single stranded DNAs with redox-tags conjugated aptamers.

Graphical abstract: An aptamer-based signal-on and multiplexed sensing platform for one-spot simultaneous electronic detection of proteins and small molecules

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Article information

DOI
https://doi.org/10.1039/C1CC10240K
Article type
Communication
Submitted
13 Jan 2011
Accepted
24 Feb 2011
First published
16 Mar 2011

Chem. Commun., 2011,47, 4733-4735

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An aptamer-based signal-on and multiplexed sensing platform for one-spot simultaneous electronic detection of proteins and small molecules

Y. Xiang, X. Qian, B. Jiang, Y. Chai and R. Yuan, Chem. Commun., 2011, 47, 4733 DOI: 10.1039/C1CC10240K

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