Issue 19, 2011
From the journal:

Chemical Communications

A supramolecular approach to the preparation of charge-tunable dendritic polycations for efficient gene delivery†

Ruijiao Dong,a   Linzhu Zhou,a   Jieli Wu,b   Chunlai Tu,a   Yue Su,a   Bangshang Zhu,b   Hongchen Gu,c   Deyue Yana  and  Xinyuan Zhu*ab  

* Corresponding authors

a School of Chemistry and Chemical Engineering, State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, People's Republic of China
E-mail: xyzhu@sjtu.edu.cn
Fax: +86 21 5474 1297
Tel: +86 21 34205699

b Instrumental Analysis Center, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, People's Republic of China

c Med-X Research Institute, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, People's Republic of China

Abstract

A facile supramolecular approach for the preparation of charge-tunable dendritic polycations, by a combination of the multi-functionality of dendritic polymers with the dynamic-tunable ability of supramolecular polymers, has been developed. It provides a new strategy for designing and developing efficient gene vectors via noncovalent interactions.

Graphical abstract: A supramolecular approach to the preparation of charge-tunable dendritic polycations for efficient gene delivery

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Article information

DOI
https://doi.org/10.1039/C1CC10934K
Article type
Communication
Submitted
17 Feb 2011
Accepted
28 Mar 2011
First published
11 Apr 2011

Chem. Commun., 2011,47, 5473-5475

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A supramolecular approach to the preparation of charge-tunable dendritic polycations for efficient gene delivery

R. Dong, L. Zhou, J. Wu, C. Tu, Y. Su, B. Zhu, H. Gu, D. Yan and X. Zhu, Chem. Commun., 2011, 47, 5473 DOI: 10.1039/C1CC10934K

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