Issue 28, 2011
From the journal:

Chemical Communications

An ultrasensitive electrochemical biosensor for detection of DNA species related to oral cancer based on nuclease-assisted target recycling and amplification of DNAzyme†

JingHua Chen,ab   Jing Zhang,a   Yang Guo,a   Juan Li,a   FengFu Fu,a   Huang-Hao Yang*a  and  Guonan Chen*a  

* Corresponding authors

a Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, Fuzhou University, Fuzhou, Fujian, China
E-mail: gnchen@fzu.edu.cn, hhyang@fzu.edu.cn
Fax: (+86)-591-22866135

b Department of Pharmaceutical Analysis, Faculty of Pharmacy, Fujian Medical University, China

Abstract

A simple, label-free, ultra-highly sensitive and selective electrochemical sensor based on nuclease-assisted target recycling and DNAzyme for the detection of DNA species related to oral cancer in saliva is developed.

Graphical abstract: An ultrasensitive electrochemical biosensor for detection of DNA species related to oral cancer based on nuclease-assisted target recycling and amplification of DNAzyme

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Article information

DOI
https://doi.org/10.1039/C1CC11929J
Article type
Communication
Submitted
06 Apr 2011
Accepted
17 May 2011
First published
14 Jun 2011

Chem. Commun., 2011,47, 8004-8006

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An ultrasensitive electrochemical biosensor for detection of DNA species related to oral cancer based on nuclease-assisted target recycling and amplification of DNAzyme

J. Chen, J. Zhang, Y. Guo, J. Li, F. Fu, H. Yang and G. Chen, Chem. Commun., 2011, 47, 8004 DOI: 10.1039/C1CC11929J

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